- Role of the environment in the interaction of nonintercalators with Z-DNA.
Role of the environment in the interaction of nonintercalators with Z-DNA.
Journal of biomolecular structure & dynamics (1989-10-01)
K E Rao, N Ramesh, D Choudhury, S K Brahmachari, V Sasisekharan
PMID2557862
ABSTRACT
Interaction of the DNA binding nonintercalators Netropsin, Distamycin and the mPD derivative with Z-DNA has been studied. It has been found that environmental factors like the solvent and added cations significantly modulate the interaction of these ligands with Z-DNA. However no definite Z to B transition in presence of these ligands was found in any case, in contrast to previously reported results (Ch. Zimmer, C. Marck and W. Guschlbauer, FEBS Lett. 154, 156-160 (1983)).