- Superparamagnetic nanoparticle-supported enzymatic resolution of racemic carboxylates.
Superparamagnetic nanoparticle-supported enzymatic resolution of racemic carboxylates.
Chemical communications (Cambridge, England) (2005-09-02)
Hari M R Gardimalla, Deendayal Mandal, Philip D Stevens, Max Yen, Yong Gao
PMID16136241
ABSTRACT
Candida rugosa lipase immobilized on maghemite nanoparticles demonstrated high stereoselectivity in kinetic resolution of racemic carboxylates and improved long-term stability over its parent free enzyme, allowing the supported enzyme to be repeatedly used for a series of chiral resolution reactions.
MATERIALS