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Case report: Helicobacter suis infection in a pig veterinarian.

Helicobacter (2013-04-05)
Myrthe Joosten, Bram Flahou, Tom Meyns, Annemieke Smet, Joris Arts, Lien De Cooman, Frank Pasmans, Richard Ducatelle, Freddy Haesebrouck
ABSTRACT

This study describes a non-Helicobacter (H.) pylori Helicobacter (NHPH) infection in a pig veterinarian. The patient suffered from reflux esophagitis and general dyspeptic symptoms and was referred to the hospital for upper gastrointestinal endoscopy. Histologic examination of corpus and antrum biopsies revealed a chronic gastritis. Large spiral-shaped non-H. pylori helicobacters could be visualized and were identified as H. suis by PCR. The patient was treated with a triple therapy, consisting of amoxicillin, clarithromycin, and pantoprazole for 10 days. Successful eradication was confirmed after a follow-up gastrointestinal endoscopy and PCR 10 weeks after treatment. A mild chronic gastritis was, however, still observed at this point in time. This case report associates porcine H. suis strains with gastric disease in humans, thus emphasizing the zoonotic importance of H. suis bacteria from pigs.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Clarithromycin, 96.0-102.0% (HPLC)
Clarithromycin for peak identification, European Pharmacopoeia (EP) Reference Standard
Clarithromycin, European Pharmacopoeia (EP) Reference Standard
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Supelco
Clarithromycin, Pharmaceutical Secondary Standard; Certified Reference Material
Supelco
Amoxicillin trihydrate, VETRANAL®, analytical standard
Supelco
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Sigma-Aldrich
Amoxicillin, 95.0-102.0% anhydrous basis