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  • Managing combined critical hypothermia, diabetic ketoacidosis and cocaine intoxication noninvasively.

Managing combined critical hypothermia, diabetic ketoacidosis and cocaine intoxication noninvasively.

The American journal of emergency medicine (2013-12-18)
Miriam Freundt, Adel Obaji, John K Hix
ABSTRACT

Severe hypothermia with a core temperature below 28°C is critical especially in patients with diabetic ketoacidosis (DKA) and carries a high risk of mortality. Our case of a 52-year-old woman presenting with DKA, pH of 6.9, potassium of 7.6 mEq/L, and body temperature of 26°C demonstrates that conservative management can be safe and successful. We used an established cardiac arrest rewarming phase protocol modified to active warming with the Meditherm 3 Machine and the facility-used rigorous DKA protocol to successfully and safely achieve rewarming without hemodialysis or extracorporeal maneuvers. Our patient arrived even more hypothermic than all previously described cases and regained normothermia and an equalized acid-base and electrolyte balance within 12 hours after admission. Eventually, no new neurologic deficit was present on discharge.

MATERIALS
Product Number
Brand
Product Description

Supelco
Cocaine hydrochloride solution, 1.0 mg/mL in methanol, analytical standard, for drug analysis
Sigma-Aldrich
Cocaine hydrochloride
Supelco
Cocaine solution, 1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®
Sigma-Aldrich
Cocaine free base