sp3-sp3 Coupling reactions in the synthesis of natural products and biologically active molecules.

sp3-sp3 Coupling reactions in the synthesis of natural products and biologically active molecules.

Natural product reports (2014-02-28)

Egor Geist, Andreas Kirschning, Thomas Schmidt

ABSTRACT

This Highlight covers the current status of relatively unexplored sp(3)-sp(3) cross-coupling reactions with particular focus on natural product and related syntheses.

MATERIALS

Product Number

Brand

Product Description

357634

Sigma-Aldrich

Nickel, wire, diam. 0.25 mm, ≥99.9%

267058

Sigma-Aldrich

Nickel, wire, diam. 0.5 mm, ≥99.99% trace metals basis

268259

Sigma-Aldrich

Nickel, foil, thickness 0.125 mm, ≥99.9%

267007

Sigma-Aldrich

Nickel, foil, thickness 0.25 mm, 99.995% trace metals basis

268283

Sigma-Aldrich

Nickel, powder, <1 μm, 99.8% trace metals basis

203904

Sigma-Aldrich

Nickel, powder, <150 μm, 99.99% trace metals basis

510033

Sigma-Aldrich

Raney^®-Nickel, W.R. Grace and Co. Raney^® 2400, slurry, in H₂O, active catalyst

510068

Sigma-Aldrich

Raney^®-Nickel, W.R. Grace and Co. Raney^® 3202, slurry, in H₂O, active catalyst

221678

Sigma-Aldrich

Raney^®-Nickel, W.R. Grace and Co. Raney^® 2800, slurry, in H₂O, active catalyst

510041

Sigma-Aldrich

Raney^®-Nickel, W.R. Grace and Co. Raney^® 4200, slurry, in H₂O, active catalyst

GF14826427

Nickel, foil, 15mm disks, thickness 0.007mm, 99.95%

GF48448952

Nickel, foil, 10mm disks, thickness 0.25mm, annealed, 99%

GF42774891

Nickel, foil, 15mm disks, thickness 0.0025mm, 99.95%

GF69167920

Nickel, rod, 100mm, diameter 3.0mm, 99%

GF70172838

Nickel, rod, 200mm, diameter 5.0mm, 99.99+%

GF90920505

Nickel, foil, 15mm disks, thickness 0.009mm, 99.95%

GF58660746

Nickel, rod, 200mm, diameter 2.0mm, 99.99+%

GF07653168

Nickel, foil, 15mm disks, thickness 0.003mm, 99.95%

GF03088627

Nickel, foil, 50mm disks, thickness 0.05mm, as rolled, 99.98%

GF78264164

Nickel, foil, 50mm disks, thickness 0.25mm, annealed, 99.98%

GF82992145

Nickel, foil, 10mm disks, thickness 0.05mm, as rolled, 99.98%

GF97332554

Nickel, rod, 200mm, diameter 16mm, 99.99+%

GF44385903

Nickel, rod, 500mm, diameter 1.5mm, 99.99+%

GF76354072

Nickel, foil, 10mm disks, thickness 0.3mm, annealed, 99%

GF83789128

Nickel, foil, 10mm disks, thickness 0.075mm, annealed, 99%

GF93936921

Nickel, foil, 10mm disks, thickness 0.5mm, as rolled, 99.99+%

GF11244259

Nickel, rod, 200mm, diameter 25.4mm, 99.98%

GF69613825

Nickel, rod, 200mm, diameter 12.0mm, 99%

GF85665842

Nickel, foil, 15mm disks, thickness 0.005mm, as rolled, 99.9%

GF08912831

Nickel, foil, 10mm disks, thickness 0.15mm, annealed, 99%