Kinetics and mechanism of oxidation of the anti-tubercular prodrug isoniazid and its analog by iridium(iv) as models for biological redox systems.

Kinetics and mechanism of oxidation of the anti-tubercular prodrug isoniazid and its analog by iridium(iv) as models for biological redox systems.

Dalton transactions (Cambridge, England : 2003) (2017-06-18)

Jingran Dong, Yanli Ren, Sufang Sun, Jiao Yang, Chunxia Nan, Hongmei Shi, Jianzhong Xu, Jie Duan, Tiesheng Shi, Lars I Elding

ABSTRACT

A complex reaction mechanism of oxidation of the anti-tubercular prodrug isoniazid (isonicotinic hydrazide, INH) by [IrCl

MATERIALS

Product Number

Brand

Product Description

Sigma-Aldrich

Sodium hexachloroiridate(IV) hexahydrate, 99.9% trace metals basis

Sigma-Aldrich

Sodium perchlorate, ACS reagent, ≥98.0%