- Translation Stress Positively Regulates MscL-Dependent Excretion of Cytoplasmic Proteins.
Translation Stress Positively Regulates MscL-Dependent Excretion of Cytoplasmic Proteins.
mBio (2018-02-01)
Rosa Morra, Francesco Del Carratore, Howbeer Muhamadali, Luminita Gabriela Horga, Samantha Halliwell, Royston Goodacre, Rainer Breitling, Neil Dixon
PMID29382730
ABSTRACT
The apparent mislocalization or excretion of cytoplasmic proteins is a commonly observed phenomenon in both bacteria and eukaryotes. However, reports on the mechanistic basis and the cellular function of this so-called "nonclassical protein secretion" are limited. Here we report that protein overexpression in recombinant cells and antibiotic-induced translation stress in wild-type
MATERIALS
Product Number
Brand
Product Description
Sigma-Aldrich
Anti-GroEL antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution