MilliporeSigma

D

Science (New York, N.Y.) (2017-10-21)
Sheng Wang, Daniel Wacker, Anat Levit, Tao Che, Robin M Betz, John D McCorvy, A J Venkatakrishnan, Xi-Ping Huang, Ron O Dror, Brian K Shoichet, Bryan L Roth
ABSTRACT

Dopamine receptors are implicated in the pathogenesis and treatment of nearly every neuropsychiatric disorder. Although thousands of drugs interact with these receptors, our molecular understanding of dopaminergic drug selectivity and design remains clouded. To illuminate dopamine receptor structure, function, and ligand recognition, we determined crystal structures of the D

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
UCSF924, ≥98% (HPLC)
Sigma-Aldrich
UCSF924NC, ≥98% (HPLC)