ABCB11
ATP-binding cassette, sub-family B (MDR/TAP), member 11
Synonyms:
ABC16, BRIC2, BSEP, PFIC-2, PFIC2, PGY4, SPGP
Species:
Human ABCB11 (8647), Mouse Abcb11 (27413), Rat Abcb11 (83569), Horse ABCB11 (100052359), domestic cat ABCB11 (101085737), dog ABCB11 (488390), chicken ABCB11 (424170), naked mole-rat Abcb11 (101716542), domestic guinea pig Abcb11 (100337637), Domestic Rabbit ABCB11 (100008767) ...More
UniProtKB ID:
Gene ID:
- Human(8647) Summary: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is the major canalicular bile salt export pump in man. Mutations in this gene cause a form of progressive familial intrahepatic cholestases which are a group of inherited disorders with severe cholestatic liver disease from early infancy. [provided by RefSeq, Jul 2008]
- Mouse(27413) ATP-binding cassette, sub-family B (MDR/TAP), member 11
- Rat(83569) ATP-binding cassette, subfamily B (MDR/TAP), member 11
- Horse(100052359) ATP-binding cassette, sub-family B (MDR/TAP), member 11
- domestic cat(101085737) ATP-binding cassette, sub-family B (MDR/TAP), member 11
- dog(488390) ATP-binding cassette, sub-family B (MDR/TAP), member 11
- chicken(424170) ATP-binding cassette, sub-family B (MDR/TAP), member 11
- naked mole-rat(101716542) ATP-binding cassette, sub-family B (MDR/TAP), member 11
- domestic guinea pig(100337637) ATP-binding cassette, sub-family B (MDR/TAP), member 11
- Domestic Rabbit(100008767) ATP-binding cassette, sub-family B (MDR/TAP), member 11
- sheep(101121238) ATP-binding cassette, sub-family B (MDR/TAP), member 11
- cow(531150) ATP-binding cassette, sub-family B (MDR/TAP), member 11
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-ABCB11 Antibody, clone 10D4.1, clone 10D4.1, from mouse,
Species Reactivity
human
Application
immunohistochemistry
western blot
western blot
Anti-ABCB11 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Monoclonal Anti-MDR3 P-Glycoprotein antibody produced in mouse, 250 μg/mL, clone P3II-26, tissue culture supernatant,
Species Reactivity
human
Application
immunocytochemistry
immunohistochemistry
western blot
immunohistochemistry
western blot
Cell Lines
Proteins
Product Number
Description
Species
SB-BSEP-Hi5, Membrane preparation for Vesicular Transport Assays, recombinant, expressed in Baculovirus infected High-5 cells,
Species
human
SB-mouseBsep-Sf9, membrane preparation for Vesicular Transport Assays, recombinant, expressed in baculovirus infected Sf9 cells,
Species
mouse
esiRNA
Product Number
Description
Species