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AMACR

alpha-methylacyl-CoA racemase

Synonyms:
AMACRD, CBAS4, RACE, RM
Species:
UniProtKB ID:
Gene ID:
  • Human(23600) Summary: This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene. [provided by RefSeq, Mar 2011]
  • Mouse(17117) alpha-methylacyl-CoA racemase
  • Rat(25284) alpha-methylacyl-CoA racemase
  • chicken(427429) alpha-methylacyl-CoA racemase
  • Horse(100054088) alpha-methylacyl-CoA racemase
  • naked mole-rat(101718677) alpha-methylacyl-CoA racemase
  • domestic guinea pig(100715601) alpha-methylacyl-CoA racemase
  • domestic cat(101081866) alpha-methylacyl-CoA racemase
  • dog(612603) alpha-methylacyl-CoA racemase
  • cow(540376) alpha-methylacyl-CoA racemase
  • sheep(101113530) alpha-methylacyl-CoA racemase

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-p504s/AMACR antibody, Rabbit monoclonal, recombinant, expressed in HEK 293 cells, clone RM349, purified immunoglobulin,
Species Reactivity
human
Application
immunohistochemistry
Anti-AMACR Antibody, clone 2A10F3, ascites fluid, clone 2A10F3, from mouse,
Species Reactivity
human
Application
immunocytochemistry
immunohistochemistry

western blot
Anti-AMACR antibody produced in rabbit, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-AMACR antibody produced in rabbit, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

western blot
Monoclonal Anti-AMACR antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL9362, purified immunoglobulin, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human AMACR, C1QTNF3-AMACR,
Species
human
MISSION® esiRNA, targeting mouse Amacr,
Species
mouse