APOBEC3A
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A
Synonyms:
A3A, ARP3, PHRBN, bK150C2.1
Species:
UniProtKB ID:
Gene ID:
- Human(200315) Summary: This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. The protein encoded by this gene lacks the zinc binding activity of other family members. The protein plays a role in immunity, by restricting transmission of foreign DNA such as viruses. One mechanism of foreign DNA restriction is deamination of foreign double-stranded DNA cytidines to uridines, which leads to DNA degradation. However, other mechanisms are also thought to be involved, as anti-viral effect is not dependent on deaminase activity. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2012]
- dog(610245) apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A
- dog(610077) DNA dC->dU-editing enzyme APOBEC-3G-like
- cow(507162) apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-APOBEC3A antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
ELISA
western blot
western blot
Anti-APOBEC3A antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunohistochemistry
immunohistochemistry
esiRNA
Product Number
Description
Species