APRT
adenine phosphoribosyltransferase
AMP, APRTD
Human APRT (353), Mouse Aprt (11821), Rat Aprt (292072), sheep APRT (101108335), cow APRT (519017), domestic cat APRT (101098913), dog APRT (479615), naked mole-rat Aprt (101713665), chicken APRT (100857155), Zebrafish aprt (393641) ...More
- Human(353) Summary: Adenine phosphoribosyltransferase belongs to the purine/pyrimidine phosphoribosyltransferase family. A conserved feature of this gene is the distribution of CpG dinucleotides. This enzyme catalyzes the formation of AMP and inorganic pyrophosphate from adenine and 5-phosphoribosyl-1-pyrophosphate (PRPP). It also produces adenine as a by-product of the polyamine biosynthesis pathway. A homozygous deficiency in this enzyme causes 2,8-dihydroxyadenine urolithiasis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(11821) adenine phosphoribosyl transferase
- Rat(292072) adenine phosphoribosyl transferase
- sheep(101108335) adenine phosphoribosyltransferase
- cow(519017) adenine phosphoribosyltransferase
- domestic cat(101098913) adenine phosphoribosyltransferase
- dog(479615) adenine phosphoribosyltransferase
- naked mole-rat(101713665) adenine phosphoribosyltransferase
- chicken(100857155) adenine phosphoribosyltransferase
- Zebrafish(393641) adenine phosphoribosyl transferase
- fruit fly(48224) Adenine phosphoribosyltransferase
- domestic guinea pig(100731502) adenine phosphoribosyltransferase
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immunohistochemistry
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