Skip to Content
MilliporeSigma

APRT

adenine phosphoribosyltransferase

Synonyms:
AMP, APRTD
Species:
UniProtKB ID:
Gene ID:
  • Human(353) Summary: Adenine phosphoribosyltransferase belongs to the purine/pyrimidine phosphoribosyltransferase family. A conserved feature of this gene is the distribution of CpG dinucleotides. This enzyme catalyzes the formation of AMP and inorganic pyrophosphate from adenine and 5-phosphoribosyl-1-pyrophosphate (PRPP). It also produces adenine as a by-product of the polyamine biosynthesis pathway. A homozygous deficiency in this enzyme causes 2,8-dihydroxyadenine urolithiasis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(11821) adenine phosphoribosyl transferase
  • Rat(292072) adenine phosphoribosyl transferase
  • sheep(101108335) adenine phosphoribosyltransferase
  • cow(519017) adenine phosphoribosyltransferase
  • domestic cat(101098913) adenine phosphoribosyltransferase
  • dog(479615) adenine phosphoribosyltransferase
  • naked mole-rat(101713665) adenine phosphoribosyltransferase
  • chicken(100857155) adenine phosphoribosyltransferase
  • Zebrafish(393641) adenine phosphoribosyl transferase
  • fruit fly(48224) Adenine phosphoribosyltransferase
  • domestic guinea pig(100731502) adenine phosphoribosyltransferase

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-APRT antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human APRT,
Species
human
MISSION® esiRNA, targeting mouse Aprt,
Species
mouse