ASL
argininosuccinate lyase
Synonyms:
ASAL
Species:
Human ASL (435), Mouse Asl (109900), Rat Asl (59085), Zebrafish asl (393423), fruit fly asl (40682), dog ASL (479704), Horse ASL (100060801), Goat ASL (100860854), cow ASL (512771), naked mole-rat Asl (101709923)
UniProtKB ID:
Gene ID:
- Human(435) Summary: This gene encodes a member of the lyase 1 family. The encoded protein forms a cytosolic homotetramer and primarily catalyzes the reversible hydrolytic cleavage of argininosuccinate into arginine and fumarate, an essential step in the liver in detoxifying ammonia via the urea cycle. Mutations in this gene result in the autosomal recessive disorder argininosuccinic aciduria, or argininosuccinic acid lyase deficiency. A nontranscribed pseudogene is also located on the long arm of chromosome 22. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
- Mouse(109900) argininosuccinate lyase
- Rat(59085) argininosuccinate lyase
- Zebrafish(393423) argininosuccinate lyase
- fruit fly(40682) asterless
- dog(479704) argininosuccinate lyase
- Horse(100060801) argininosuccinate lyase
- Goat(100860854) argininosuccinate lyase
- cow(512771) argininosuccinate lyase
- naked mole-rat(101709923) argininosuccinate lyase
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-ASL antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
western blot
Anti-ASL (AB1) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, goat, guinea pig, horse, human, mouse, rabbit, rat
Application
western blot
Anti-ASL antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot