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MilliporeSigma

BAK1

BCL2-antagonist/killer 1

Synonyms:
BAK, BAK-LIKE, BCL2L7, CDN1
Species:
UniProtKB ID:
Gene ID:
  • Human(578) Summary: The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress. [provided by RefSeq, Jul 2008]
  • Mouse(12018) BCL2-antagonist/killer 1
  • Rat(116502) BCL2-antagonist/killer 1
  • Thale Cress(829480) Leu-rich receptor Serine/threonine protein kinase BAK1
  • chicken(419912) BCL2-antagonist/killer 1
  • dog(481744) BCL2-antagonist/killer 1
  • domestic guinea pig(100734553) BCL2-antagonist/killer 1
  • cow(514090) BCL2-antagonist/killer 1
  • domestic cat(101093435) BCL2-antagonist/killer 1
  • domestic cat(768278) BCL2-antagonist/killer 1

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

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  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-BAK antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse
Application
ELISA
immunohistochemistry

western blot
Anti-Bak antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
human
Application
immunohistochemistry
microarray

western blot
ANTI-BAK (BH3 DOMAIN SPECIFIC) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-Bak Antibody, clone 7Q3T8, Rabbit Monoclonal, ,
Species Reactivity
mouse
Application
immunohistochemistry
western blot
Anti-Bak Antibody, clone 2D18 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human, mouse, rat
Application
immunocytochemistry
immunohistochemistry

western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human BAK1,
Species
human