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BHMT2

betaine--homocysteine S-methyltransferase 2

Synonyms:
Species:
UniProtKB ID:
Gene ID:
  • Human(23743) Summary: Homocysteine is a sulfur-containing amino acid that plays a crucial role in methylation reactions. Transfer of the methyl group from betaine to homocysteine creates methionine, which donates the methyl group to methylate DNA, proteins, lipids, and other intracellular metabolites. The protein encoded by this gene is one of two methyl transferases that can catalyze the transfer of the methyl group from betaine to homocysteine. Anomalies in homocysteine metabolism have been implicated in disorders ranging from vascular disease to neural tube birth defects such as spina bifida. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2010]
  • Mouse(64918) betaine-homocysteine methyltransferase 2
  • Rat(365972) betaine-homocysteine S-methyltransferase 2
  • cow(616683) betaine--homocysteine S-methyltransferase 2
  • domestic cat(101084933) betaine--homocysteine S-methyltransferase 2
  • Horse(100073266) betaine--homocysteine S-methyltransferase 2
  • domestic guinea pig(100718920) betaine--homocysteine S-methyltransferase 2
  • dog(488934) betaine--homocysteine S-methyltransferase 2
  • sheep(101108575) betaine--homocysteine S-methyltransferase 2
  • naked mole-rat(101720782) betaine--homocysteine S-methyltransferase 2

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-BHMT2 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-BHMT2 antibody produced in mouse, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-BHMT2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
Monoclonal Anti-BHMT2, (N-terminal) antibody produced in mouse, clone 1E8, ascites fluid,
Species Reactivity
human
Application
ELISA
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human BHMT2,
Species
human
MISSION® esiRNA, targeting mouse Bhmt2,
Species
mouse

Small Molecule - Substrate

Product Number
Description
Species
Betaine hydrochloride, ≥99%,
Species
human
Betaine hydrochloride, United States Pharmacopeia (USP) Reference Standard,
Species
human
Betaine hydrochloride, certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland,
Species
human