BUB1
BUB1 mitotic checkpoint serine/threonine kinase
Synonyms:
BUB1A, BUB1L, hBUB1
Species:
Human BUB1 (699), Mouse Bub1 (12235), Rat Bub1 (296137), Zebrafish bub1 (100307076), Domestic Rabbit BUB1 (100352234), sheep BUB1 (101117404), cow BUB1 (514777), Horse BUB1 (100064049), domestic cat BUB1 (101085035), dog BUB1 (100682599) ...More
UniProtKB ID:
Gene ID:
- Human(699) Summary: This gene encodes a serine/threonine-protein kinase that play a central role in mitosis. The encoded protein functions in part by phosphorylating members of the mitotic checkpoint complex and activating the spindle checkpoint. This protein also plays a role in inhibiting the activation of the anaphase promoting complex/cyclosome. This protein may also function in the DNA damage response. Mutations in this gene have been associated with aneuploidy and several forms of cancer. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
- Mouse(12235) budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae)
- Rat(296137) BUB1 mitotic checkpoint serine/threonine kinase
- Zebrafish(100307076) BUB1 mitotic checkpoint serine/threonine kinase
- Domestic Rabbit(100352234) budding uninhibited by benzimidazoles 1 homolog (yeast)
- sheep(101117404) budding uninhibited by benzimidazoles 1 homolog (yeast)
- cow(514777) budding uninhibited by benzimidazoles 1 homolog (yeast)
- Horse(100064049) budding uninhibited by benzimidazoles 1 homolog (yeast)
- domestic cat(101085035) budding uninhibited by benzimidazoles 1 homolog (yeast)
- dog(100682599) budding uninhibited by benzimidazoles 1 homolog (yeast)
- chicken(421226) budding uninhibited by benzimidazoles 1 homolog (yeast)
- domestic guinea pig(100725012) BUB1 mitotic checkpoint serine/threonine kinase
- naked mole-rat(101724275) BUB1 mitotic checkpoint serine/threonine kinase
- fruit fly(33758) Bub1 homologue
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-Bub1 Antibody, clone 14H5, clone 14H5, Chemicon®, from mouse,
Species Reactivity
human, primate
Application
immunocytochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
esiRNA
Product Number
Description
Species