CASP10
caspase 10, apoptosis-related cysteine peptidase
Synonyms:
ALPS2, FLICE2, MCH4
Species:
Human CASP10 (843), cow CASP10 (100848685), chicken CASP10 (424081), domestic cat CASP10 (101085995), naked mole-rat Casp10 (101712620), domestic guinea pig Casp10 (100717714), Horse CASP10 (100068201), dog CASP10 (488472)
UniProtKB ID:
Gene ID:
- Human(843) Summary: This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 3 and 7, and the protein itself is processed by caspase 8. Mutations in this gene are associated with type IIA autoimmune lymphoproliferative syndrome, non-Hodgkin lymphoma and gastric cancer. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Apr 2011]
- cow(100848685) caspase 10, apoptosis-related cysteine peptidase
- chicken(424081) caspase 10, apoptosis-related cysteine peptidase
- domestic cat(101085995) caspase 10, apoptosis-related cysteine peptidase
- naked mole-rat(101712620) caspase 10, apoptosis-related cysteine peptidase
- domestic guinea pig(100717714) caspase 10, apoptosis-related cysteine peptidase
- Horse(100068201) caspase 10, apoptosis-related cysteine peptidase
- dog(488472) caspase 10, apoptosis-related cysteine peptidase
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-Caspase-10 Antibody, from rabbit, purified by affinity chromatography,
Species Reactivity
human
Application
western blot
Anti-CASP10 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
ELISA
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
Monoclonal Anti-CASP10, (N-terminal) antibody produced in mouse, clone 2E7, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence
western blot
immunofluorescence
western blot
Anti-CASP10 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
western blot
Monoclonal Anti-CASP10 antibody produced in mouse, clone 1D8, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
proximity ligation assay
proximity ligation assay
Small Molecule - Inhibitor
Product Number
Description
Species
Proteins
Product Number
Description
Species
Caspase 10 human, >90% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder, 8,000 units/mg protein (Bradford),
Species
human
esiRNA
Product Number
Description
Species