CASP2
caspase 2, apoptosis-related cysteine peptidase
Synonyms:
CASP-2, ICH1, NEDD-2, NEDD2, PPP1R57
Species:
Human CASP2 (835), Mouse Casp2 (12366), Rat Casp2 (64314), dog CASP2 (482737), Zebrafish casp2 (373118), chicken CASP2 (395857), naked mole-rat Casp2 (101712106), domestic guinea pig Casp2 (100735399), cow CASP2 (531419), sheep CASP2 (101115025)
UniProtKB ID:
Gene ID:
- Human(835) Summary: This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates. The encoded protein may function in stress-induced cell death pathways, cell cycle maintenance, and the suppression of tumorigenesis. Increased expression of this gene may play a role in neurodegenerative disorders including Alzheimer's disease, Huntington's disease and temporal lobe epilepsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]
- Mouse(12366) caspase 2
- Rat(64314) caspase 2
- dog(482737) caspase 2, apoptosis-related cysteine peptidase
- Zebrafish(373118) caspase 2, apoptosis-related cysteine protease
- chicken(395857) caspase 2, apoptosis-related cysteine peptidase
- naked mole-rat(101712106) caspase 2, apoptosis-related cysteine peptidase
- domestic guinea pig(100735399) caspase 2, apoptosis-related cysteine peptidase
- cow(531419) caspase 2, apoptosis-related cysteine peptidase
- sheep(101115025) caspase 2, apoptosis-related cysteine peptidase
- domestic cat(101088318) caspase 2, apoptosis-related cysteine peptidase
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-Caspase-2 Antibody, clone 2Z10F1, Rabbit Monoclonal, ,
Species Reactivity
human, rat
Application
western blot
Anti-Caspase 2 Antibody, clone 10C6, clone 10C6, Chemicon®, from rat,
Species Reactivity
canine, human, monkey, mouse
Application
ELISA
flow cytometry
immunoprecipitation (IP)
western blot
flow cytometry
immunoprecipitation (IP)
western blot
Anti-CASP2 (p18, Cleaved-Gly170) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
ELISA
western blot
western blot
Monoclonal Anti-CASP2 antibody produced in mouse, clone 1C11, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence
western blot
immunofluorescence
western blot
Anti-Caspase 2 Antibody, clone 11B4, clone 11B4, Chemicon®, from rat,
Species Reactivity
canine, human, monkey, mouse
Application
ELISA
flow cytometry
immunoprecipitation (IP)
western blot
flow cytometry
immunoprecipitation (IP)
western blot
Small Molecule - Inhibitor
Product Number
Description
Species