CD3E
CD3e molecule, epsilon (CD3-TCR complex)
T3E, TCRE
Human CD3E (916), Mouse Cd3e (12501), Rat Cd3e (315609), domestic cat CD3E (493936), naked mole-rat Cd3e (101711464), dog CD3E (442981), sheep CD3E (443437), Domestic Rabbit CD3E (100008616), domestic guinea pig Cd3e (100727781), cow CD3E (281054)
- Human(916) Summary: The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq, Jul 2008]
- Mouse(12501) CD3 antigen, epsilon polypeptide
- Rat(315609) CD3 molecule, epsilon
- domestic cat(493936) CD3e molecule, epsilon (CD3-TCR complex)
- naked mole-rat(101711464) CD3e molecule, epsilon (CD3-TCR complex)
- dog(442981) CD3e molecule, epsilon (CD3-TCR complex)
- sheep(443437) CD3e molecule, epsilon (CD3-TCR complex)
- Domestic Rabbit(100008616) CD3e molecule, epsilon (CD3-TCR complex)
- domestic guinea pig(100727781) CD3e molecule, epsilon (CD3-TCR complex)
- cow(281054) CD3e molecule, epsilon (CD3-TCR complex)
- chicken(396062) CD3e molecule, epsilon (CD3-TCR complex)
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