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Merck

CD74

CD74 molecule, major histocompatibility complex, class II invariant chain

同義詞:
DHLAG, HLADG, II, Ia-GAMMA
物種:
Human CD74 (972), Mouse Cd74 (16149), Rat Cd74 (25599), cow CD74 (613384), domestic cat CD74 (101085953), domestic guinea pig Cd74 (100735496), dog CD74 (479329), sheep CD74 (101102561), chicken CD74 (414741), naked mole-rat Cd74 (101723625)
UniProtKB ID:
P04233, A8K7R1, B4DNE8, D3DQG3, D3DQG4, Q14597, Q29832, Q5U0J8
基因 ID:
  • Human(972) Summary: The protein encoded by this gene associates with class II major histocompatibility complex (MHC) and is an important chaperone that regulates antigen presentation for immune response. It also serves as cell surface receptor for the cytokine macrophage migration inhibitory factor (MIF) which, when bound to the encoded protein, initiates survival pathways and cell proliferation. This protein also interacts with amyloid precursor protein (APP) and suppresses the production of amyloid beta (Abeta). Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011]
  • Mouse(16149) CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)
  • Rat(25599) Cd74 molecule, major histocompatibility complex, class II invariant chain
  • cow(613384) CD74 molecule, major histocompatibility complex, class II invariant chain
  • domestic cat(101085953) CD74 molecule, major histocompatibility complex, class II invariant chain
  • domestic guinea pig(100735496) CD74 molecule, major histocompatibility complex, class II invariant chain
  • dog(479329) CD74 molecule, major histocompatibility complex, class II invariant chain
  • sheep(101102561) CD74 molecule, major histocompatibility complex, class II invariant chain
  • chicken(414741) CD74 molecule, major histocompatibility complex, class II invariant chain
  • naked mole-rat(101723625) CD74 molecule, major histocompatibility complex, class II invariant chain

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Antibodies

產品編號
描述
物種活性
應用
HPA010592
Anti-CD74 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物種活性
human
應用
immunohistochemistry
western blot
MABF33
抗-MHC II类（I-A/I-E）抗体，克隆M5/114, clone M5/114, from rat,
物種活性
mouse
應用
flow cytometry
immunohistochemistry
western blot
MABF80D
Anti-MHC class II (I-A/I-E), FITC, clone M5/114 .15.2 Antibody, clone M5/114.15.2, from rat, FITC conjugate,
物種活性
mouse
應用
flow cytometry