Skip to Content
MilliporeSigma

CFL2

cofilin 2 (muscle)

Synonyms:
NEM7
Species:
UniProtKB ID:
Gene ID:
  • Human(1073) Summary: This gene encodes an intracellular protein that is involved in the regulation of actin-filament dynamics. This protein is a major component of intranuclear and cytoplasmic actin rods. It can bind G- and F-actin in a 1:1 ratio of cofilin to actin, and it reversibly controls actin polymerization and depolymerization in a pH-dependent manner. Mutations in this gene cause nemaline myopathy type 7, a form of congenital myopathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2009]
  • Mouse(12632) cofilin 2, muscle
  • Rat(366624) cofilin 2, muscle
  • Zebrafish(403001) cofilin 2 (muscle)
  • domestic cat(101083089) cofilin 2 (muscle)
  • cow(539332) cofilin 2 (muscle)
  • domestic guinea pig(100727405) cofilin 2 (muscle)
  • dog(490649) cofilin 2 (muscle)
  • sheep(101118388) cofilin 2 (muscle)
  • chicken(423320) cofilin 2 (muscle)

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-Cofilin antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
western blot
Monoclonal Anti-CFL2 antibody produced in mouse, clone 6G9, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-Cofilin 2 Antibody, Upstate®, from rabbit,
Species Reactivity
human, rat
Application
western blot
Anti-phospho-Cofilin 2 (Ser3) Antibody, Upstate®, from rabbit,
Species Reactivity
chicken, human, mouse
Application
western blot
Anti-CFL2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Cfl2,
Species
mouse
MISSION® esiRNA, targeting human CFL2,
Species
human