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MilliporeSigma

CHMP4C

charged multivesicular body protein 4C

Synonyms:
SNF7-3, Shax3, VPS32C
Species:
UniProtKB ID:
Gene ID:
  • Human(92421) Summary: CHMP4C belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 [PubMed 16730941]
  • Mouse(66371) charged multivesicular body protein 4C
  • Rat(361916) charged multivesicular body protein 4C
  • domestic guinea pig(100723062) charged multivesicular body protein 4C
  • sheep(101119649) charged multivesicular body protein 4C
  • dog(477926) charged multivesicular body protein 4C
  • domestic cat(101089076) charged multivesicular body protein 4C
  • chicken(420201) chromatin modifying protein 4C
  • cow(507572) charged multivesicular body protein 4C
  • Zebrafish(550542) chromatin modifying protein 4C
  • naked mole-rat(101704056) charged multivesicular body protein 4C

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

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  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-CHMP4C antibody produced in rabbit, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-CHMP4C antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Chmp4c,
Species
mouse
MISSION® esiRNA, targeting human CHMP4C,
Species
human