CHN2
chimerin 2
Synonyms:
ARHGAP3, BCH, CHN2-3, RHOGAP3
Species:
Human CHN2 (1124), Mouse Chn2 (69993), Rat Chn2 (84031), domestic cat CHN2 (101093762), Domestic Rabbit CHN2 (100344407), dog CHN2 (475267), Zebrafish chn2 (570999), domestic guinea pig Chn2 (100723720), naked mole-rat Chn2 (101701673), chicken CHN2 (428437) ...More
UniProtKB ID:
Gene ID:
- Human(1124) Summary: This gene is a member of the chimerin family and encodes a protein with a phorbol-ester/DAG-type zinc finger, a Rho-GAP domain and an SH2 domain. This protein has GTPase-activating protein activity that is regulated by phospholipid binding and binding of diacylglycerol (DAG) induces translocation of the protein from the cytosol to the Golgi apparatus membrane. The protein plays a role in the proliferation and migration of smooth muscle cells. Decreased expression of this gene is associated with high-grade gliomas and breast tumors, and increased expression of this gene is associated with lymphomas. Mutations in this gene have been associated with schizophrenia in men. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
- Mouse(69993) chimerin (chimaerin) 2
- Rat(84031) chimerin 2
- domestic cat(101093762) chimerin 2
- Domestic Rabbit(100344407) chimerin 2
- dog(475267) chimerin 2
- Zebrafish(570999) chimerin (chimaerin) 2
- domestic guinea pig(100723720) chimerin 2
- naked mole-rat(101701673) chimerin 2
- chicken(428437) chimerin (chimaerin) 2
- cow(507285) chimerin (chimaerin) 2
- sheep(101103716) chimerin 2
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-CHN2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
Anti-CHN2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-CHN2 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, horse, human, mouse, rabbit, rat
Application
western blot
esiRNA
Product Number
Description
Species