CHRM1
cholinergic receptor, muscarinic 1
Synonyms:
HM1, M1, M1R
Species:
Human CHRM1 (1128), Mouse Chrm1 (12669), Rat Chrm1 (25229), domestic guinea pig Chrm1 (100728041), domestic cat CHRM1 (493664), domestic cat CHRM1 (101093801), dog CHRM1 (483776), sheep CHRM1 (101117029), cow CHRM1 (281684), Horse CHRM1 (100064117)
UniProtKB ID:
Gene ID:
- Human(1128) Summary: The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 1 is involved in mediation of vagally-induced bronchoconstriction and in the acid secretion of the gastrointestinal tract. The gene encoding this receptor is localized to 11q13. [provided by RefSeq, Jul 2008]
- Mouse(12669) cholinergic receptor, muscarinic 1, CNS
- Rat(25229) cholinergic receptor, muscarinic 1
- domestic guinea pig(100728041) cholinergic receptor, muscarinic 1
- domestic cat(493664) cholinergic receptor, muscarinic 1
- domestic cat(101093801) cholinergic receptor, muscarinic 1
- dog(483776) cholinergic receptor, muscarinic 1
- sheep(101117029) cholinergic receptor, muscarinic 1
- cow(281684) cholinergic receptor, muscarinic 1
- Horse(100064117) cholinergic receptor, muscarinic 1
- naked mole-rat(101702102) cholinergic receptor, muscarinic 1
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Small Molecule - Agonist
Product Number
Description
Species
Pilocarpine nitrate for system suitability, European Pharmacopoeia (EP) Reference Standard,
Species
human
Pilocarpine Hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human
Small Molecule - Antagonist
Product Number
Description
Species
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-CHRM1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-CHRM1 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
western blot
western blot
Anti-Muscarinic Acetylcholine Receptor m1 Antibody, Chemicon®, from rabbit,
Species Reactivity
mouse, rat
Application
immunohistochemistry
western blot
western blot
Anti-Muscarinic Acetylcholine Receptor (M1) antibody produced in rabbit, affinity isolated antibody, lyophilized powder,
Species Reactivity
mouse, rat
Application
immunohistochemistry
western blot
western blot
Small Molecule - Inhibitor
Product Number
Description
Species
Doxepin hydrochloride, ~85% E-isomer basis, ≥98% (GC), 15% Z-isomer basis, powder,
Species
human
Small Molecule - Ligand
Proteins
Product Number
Description
Species
ChemiScreen Membrane Preparation Human Recombinant M1 Muscarinic Acetylcholine Receptor, Human M1 GPCR membrane prepation for Radioligand binding Assays.,
Species
human
esiRNA
Product Number
Description
Species