P127

(+)-Pentazocine

solid

• Empirical Formula (Hill Notation): C₁₉H₂₇NO
• CAS Number: 7361-76-4
• Molecular Weight: 285.42
• UNSPSC Code: 12352200
• PubChem Substance ID: 24898179
• NACRES: NA.77

Properties

• form: solid
• Quality Level: 100
• optical activity: [α]23/D +134.6°, c = 1 in chloroform(lit.)
• drug control: USDEA Schedule IV; Home Office Schedule 3; stupéfiant (France); kontrollierte Droge in Deutschland; regulated under CDSA - not available from Sigma-Aldrich Canada; psicótropo (Spain); Decreto Lei 15/93: Tabela IIC (Portugal); kontrollierte Droge in Deutschland
• color: white
• originator: Sanofi Aventis
• SMILES string: [H][C@@]12Cc3ccc(O)cc3[C@@](C)(CCN1C\C=C(\C)C)[C@@H]2C
• InChI: 1S/C19H27NO/c1-13(2)7-9-20-10-8-19(4)14(3)18(20)11-15-5-6-16(21)12-17(15)19/h5-7,12,14,18,21H,8-11H2,1-4H3/t14-,18+,19+/m1/s1
• InChI key: VOKSWYLNZZRQPF-CCKFTAQKSA-N
• Gene Information: human ... EBP(10682) ; rat ... Chrm1(25229), Chrm2(81645), Drd2(24318), Oprm1(25601)

Description

Biochem/physiol Actions

σ receptor agonist; active enantiomer of pentazocine.

Features and Benefits

This compound was developed by Sanofi Aventis. To browse the list of other pharma-developed compounds, Approved Drugs, and Drug Candidates, click here.

Preparation Note

A 10 mM solution of (+)-pentazocine is prepared by warming 28.5 mg of (+)-pentazocine free base in 2 mL of 0.1N HCl with shaking or sonication. When all solids have dissolved, the solution is cooled to room temperature and diluted with 10 mL of pH 7 buffer. Solutions should be freshly prepared, since cooling below room temperature may result in precipitation.

Legal Information

German
Dieses Produkt fällt unter das Betäubungsmittelgesetz (BtMG). Für eine Bestellung dieses Produktes ist eine Erlaubnis nach § 3 BtMG zwingend erforderlich, es sei denn, es greift eine Ausnahme von der Erlaubnispflicht nach § 4 oder § 26 BtMG.

English
This product is subject to the German Narcotics Act. A permit under Section 3 of the German Narcotics Act is mandatory for ordering this product unless an exemption from the permit requirement under Section 4 or Section 26 of the German Narcotics Act applies.

Disclaimer

Photosensitive

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H302 + H312 + H332
• pcodes: P261 - P264 - P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P312
• Hazard Classifications: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves