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CNTNAP2

contactin associated protein-like 2

Synonyms:
AUTS15, CASPR2, CDFE, NRXN4, PTHSL1
Species:
UniProtKB ID:
Gene ID:
  • Human(26047) Summary: This gene encodes a member of the neurexin family which functions in the vertebrate nervous system as cell adhesion molecules and receptors. This protein, like other neurexin proteins, contains epidermal growth factor repeats and laminin G domains. In addition, it includes an F5/8 type C domain, discoidin/neuropilin- and fibrinogen-like domains, thrombospondin N-terminal-like domains and a putative PDZ binding site. This protein is localized at the juxtaparanodes of myelinated axons, and mediates interactions between neurons and glia during nervous system development and is also involved in localization of potassium channels within differentiating axons. This gene encompasses almost 1.5% of chromosome 7 and is one of the largest genes in the human genome. It is directly bound and regulated by forkhead box protein P2 (FOXP2), a transcription factor related to speech and language development. This gene has been implicated in multiple neurodevelopmental disorders, including Gilles de la Tourette syndrome, schizophrenia, epilepsy, autism, ADHD and mental retardation.[provided by RefSeq, Mar 2010]
  • Mouse(66797) contactin associated protein-like 2
  • Rat(500105) contactin associated protein-like 2
  • Horse(100060296) contactin associated protein-like 2
  • Domestic Rabbit(100354524) contactin associated protein-like 2
  • chicken(768456) contactin associated protein-like 2
  • sheep(101106322) contactin associated protein-like 2
  • dog(100687859) contactin associated protein-like 2
  • domestic cat(101086795) contactin associated protein-like 2
  • cow(100337375) contactin associated protein-like 2
  • cow(516395) contactin associated protein-like 2
  • domestic guinea pig(100717858) contactin associated protein-like 2

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ELISA

Product Number
Description
Species
Human Caspr2 ELISA, for serum, plasma and cell culture supernatants,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-CNTNAP2 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-CNTNAP2 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-CNTNAP2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-Caspr2 Antibody, extracellular domain, serum, from rabbit,
Species Reactivity
human, mouse
Application
immunocytochemistry
western blot
Anti-Caspr2 antibody produced in rabbit, affinity isolated antibody, lyophilized powder,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Cntnap2,
Species
mouse
MISSION® esiRNA, targeting human CNTNAP2,
Species
human