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CPB2

carboxypeptidase B2 (plasma)

Synonyms:
CPU, PCPB, TAFI
Species:
UniProtKB ID:
Gene ID:
  • Human(1361) Summary: Carboxypeptidases are enzymes that hydrolyze C-terminal peptide bonds. The carboxypeptidase family includes metallo-, serine, and cysteine carboxypeptidases. According to their substrate specificity, these enzymes are referred to as carboxypeptidase A (cleaving aliphatic residues) or carboxypeptidase B (cleaving basic amino residues). The protein encoded by this gene is activated by trypsin and acts on carboxypeptidase B substrates. After thrombin activation, the mature protein downregulates fibrinolysis. Polymorphisms have been described for this gene and its promoter region. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013]
  • Mouse(56373) carboxypeptidase B2 (plasma)
  • Rat(113936) carboxypeptidase B2 (plasma)
  • domestic guinea pig(100736054) carboxypeptidase B2 (plasma)
  • cow(508222) carboxypeptidase B2 (plasma)
  • dog(608910) carboxypeptidase B2 (plasma)
  • naked mole-rat(101712343) carboxypeptidase B2 (plasma)
  • domestic cat(101082116) carboxypeptidase B2 (plasma)
  • chicken(418851) carboxypeptidase B2 (plasma)
  • sheep(101112329) carboxypeptidase B2 (plasma)
  • Zebrafish(100000935) carboxypeptidase B2 (plasma)

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-CPB2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-CPB2 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-CPB2 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot

Proteins

Product Number
Description
Species
CARBOXYPEPTIDASE-B rat, recombinant, expressed in E. coli, ≥95% (SDS-PAGE), ≥95% (HPLC),
Species
rat

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Cpb2,
Species
mouse
MISSION® esiRNA, targeting human CPB2,
Species
human