CXCR4
chemokine (C-X-C motif) receptor 4
Synonyms:
CD184, D2S201E, FB22, HM89, HSY3RR, LAP3, LCR1, LESTR, NPY3R, NPYR, NPYRL, NPYY3R, WHIM
Species:
Human CXCR4 (7852), Mouse Cxcr4 (12767), Rat Cxcr4 (60628), cow CXCR4 (281736), domestic guinea pig Cxcr4 (100731341), dog CXCR4 (483900), naked mole-rat Cxcr4 (101699254), sheep CXCR4 (443532), chicken CXCR4 (395324), Domestic Rabbit CXCR4 (100346189)
UniProtKB ID:
Gene ID:
- Human(7852) Summary: This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
- Mouse(12767) chemokine (C-X-C motif) receptor 4
- Rat(60628) chemokine (C-X-C motif) receptor 4
- cow(281736) chemokine (C-X-C motif) receptor 4
- domestic guinea pig(100731341) chemokine (C-X-C motif) receptor 4
- dog(483900) chemokine (C-X-C motif) receptor 4
- naked mole-rat(101699254) chemokine (C-X-C motif) receptor 4
- sheep(443532) neuropeptide Y receptor type 3
- chicken(395324) chemokine (C-X-C motif) receptor 4
- Domestic Rabbit(100346189) chemokine (C-X-C motif) receptor 4
- domestic cat(493676) chemokine (C-X-C motif) receptor 4
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-CXCR4 (Fusin) (182-196) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-phospho-CXCR4 (pSer339) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
Anti-CXCR4-Lo antibody produced in rabbit, purified immunoglobulin (IgG),
Species Reactivity
Application
immunocytochemistry
immunofluorescence
western blot
immunofluorescence
western blot
Anti-CXCR4 Antibody, clone 12G5, clone 12G5, from mouse,
Species Reactivity
human
Application
flow cytometry
immunocytochemistry
neutralization
immunocytochemistry
neutralization
Anti-CXCR4 Antibody, clone 9B6G1, Rabbit Monoclonal, ,
Species Reactivity
human
Application
western blot
Proteins
Product Number
Description
Species
ChemiSCREEN CXCR4 Membrane Preparation, Human CXCR4 GPCR membrane preparation for Radioligand binding Assays & GTPgammaS binding.,
Species
human