CYP2B6
cytochrome P450, family 2, subfamily B, polypeptide 6
Synonyms:
CPB6, CYP2B, CYP2B7, CYP2B7P, CYPIIB6, EFVM, IIB1, P450
Species:
UniProtKB ID:
Gene ID:
- Human(1555) Summary: This gene, CYP2B6, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to metabolize some xenobiotics, such as the anti-cancer drugs cyclophosphamide and ifosphamide. Transcript variants for this gene have been described; however, it has not been resolved whether these transcripts are in fact produced by this gene or by a closely related pseudogene, CYP2B7. Both the gene and the pseudogene are located in the middle of a CYP2A pseudogene found in a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q. [provided by RefSeq, Jul 2008]
- dog(474177) cytochrome P450 2B11
- cow(504769) cytochrome P450 subfamily 2B
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-Cytochrome P450 2B6 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
ELISA
western blot
western blot
Anti-CYP2B6 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
Anti-CYP2B6 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
western blot
Cell Lines
Product Number
Description
Species