DDIT3
DNA-damage-inducible transcript 3
Synonyms:
CEBPZ, CHOP, CHOP-10, CHOP10, GADD153
Species:
Human DDIT3 (1649), Mouse Ddit3 (13198), Rat Ddit3 (29467), cow DDIT3 (777788), domestic guinea pig Ddit3 (101787388), chicken DDIT3 (100857832), Zebrafish ddit3 (561924), domestic cat DDIT3 (101081819), sheep DDIT3 (541600), dog DDIT3 (607439)
UniProtKB ID:
Gene ID:
- Human(1649) Summary: This gene encodes a member of the CCAAT/enhancer-binding protein (C/EBP) family of transcription factors. The protein functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members, such as C/EBP and LAP (liver activator protein), and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis, is activated by endoplasmic reticulum stress, and promotes apoptosis. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in myxoid liposarcomas or Ewing sarcoma. Multiple alternatively spliced transcript variants encoding two isoforms with different length have been identified. [provided by RefSeq, Aug 2010]
- Mouse(13198) DNA-damage inducible transcript 3
- Rat(29467) DNA-damage inducible transcript 3
- cow(777788) DNA-damage-inducible transcript 3
- domestic guinea pig(101787388) DNA-damage-inducible transcript 3
- chicken(100857832) DNA-damage-inducible transcript 3
- Zebrafish(561924) DNA-damage-inducible transcript 3
- domestic cat(101081819) DNA-damage-inducible transcript 3
- sheep(541600) DNA-damage-inducible transcript 3
- dog(607439) DNA-damage-inducible transcript 3
- naked mole-rat(101715873) DNA-damage-inducible transcript 3
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-CHOP, N-Terminal antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse
Application
ELISA
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
Anti-DDIT3 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-GADD153/DDIT3 Antibody, clone 3I18 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human, mouse, rat
Application
ELISA
affinity binding assay
western blot
affinity binding assay
western blot
Anti-DDIT3/CHOP antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
western blot
Anti-DDIT3/CHOP antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot