跳轉至內容
Merck

DDIT3

DNA-damage-inducible transcript 3

同義詞:
CEBPZ, CHOP, CHOP-10, CHOP10, GADD153
物種:
UniProtKB ID:
基因 ID:
  • Human(1649) Summary: This gene encodes a member of the CCAAT/enhancer-binding protein (C/EBP) family of transcription factors. The protein functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members, such as C/EBP and LAP (liver activator protein), and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis, is activated by endoplasmic reticulum stress, and promotes apoptosis. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in myxoid liposarcomas or Ewing sarcoma. Multiple alternatively spliced transcript variants encoding two isoforms with different length have been identified. [provided by RefSeq, Aug 2010]
  • Mouse(13198) DNA-damage inducible transcript 3
  • Rat(29467) DNA-damage inducible transcript 3
  • cow(777788) DNA-damage-inducible transcript 3
  • domestic guinea pig(101787388) DNA-damage-inducible transcript 3
  • chicken(100857832) DNA-damage-inducible transcript 3
  • Zebrafish(561924) DNA-damage-inducible transcript 3
  • domestic cat(101081819) DNA-damage-inducible transcript 3
  • sheep(541600) DNA-damage-inducible transcript 3
  • dog(607439) DNA-damage-inducible transcript 3
  • naked mole-rat(101715873) DNA-damage-inducible transcript 3

Custom & Knockdown Gene Products

Antibodies

產品編號
描述
物種活性
應用
Anti-GADD153/DDIT3/CHOP Antibody, from rabbit, purified by affinity chromatography,
物種活性
bovine, human, monkey, mouse, porcine, rat
應用
western blot
抗-CHOP,N端子 兔抗, affinity isolated antibody,
物種活性
human, mouse
應用
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-GADD153 antibody produced in rabbit, affinity isolated antibody,
物種活性
human, mouse, rat
應用
ELISA
immunofluorescence

immunohistochemistry

western blot
Monoclonal Anti-DDIT3 antibody produced in mouse, clone 2C4, purified immunoglobulin, buffered aqueous solution,
物種活性
human
應用
ELISA
western blot
Anti-GADD153 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
物種活性
human
應用
immunocytochemistry
microarray

western blot