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DMAP1

DNA methyltransferase 1 associated protein 1

Synonyms:
DNMAP1, DNMTAP1, EAF2, MEAF2, SWC4
Species:
UniProtKB ID:
Gene ID:
  • Human(55929) Summary: This gene encodes a subunit of several, distinct complexes involved in the repression or activation of transcription. The encoded protein can independently repress transcription and is targeted to replication foci throughout S phase by interacting directly with the N-terminus of DNA methyltransferase 1. During late S phase, histone deacetylase 2 is added to this complex, providing a means to deacetylate histones in transcriptionally inactive heterochromatin following replication. The encoded protein is also a component of the nucleosome acetyltransferase of H4 complex and interacts with the transcriptional corepressor tumor susceptibility gene 101 and the pro-apoptotic death-associated protein 6, among others. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2008]
  • Mouse(66233) DNA methyltransferase 1-associated protein 1
  • Rat(298447) DNA methyltransferase 1-associated protein 1
  • fruit fly(37339) CG11132 gene product from transcript CG11132-RA
  • chicken(424578) DNA methyltransferase 1 associated protein 1
  • cow(508127) DNA methyltransferase 1 associated protein 1
  • dog(475385) DNA methyltransferase 1 associated protein 1
  • Domestic Rabbit(100350915) DNA methyltransferase 1 associated protein 1
  • sheep(101115583) DNA methyltransferase 1 associated protein 1
  • naked mole-rat(101725928) DNA methyltransferase 1 associated protein 1
  • domestic guinea pig(100720826) DNA methyltransferase 1 associated protein 1
  • Zebrafish(393225) DNA methyltransferase 1 associated protein 1
  • domestic cat(101085736) DNA methyltransferase 1 associated protein 1

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Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-DMAP1 antibody produced in mouse, clone 2G12, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
Monoclonal Anti-DMAP1, (N-terminal) antibody produced in mouse, clone 5H4, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
Anti-DMAP1 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
immunofluorescence
western blot
Anti-DMAP1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
Anti-DMAP1 antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human DMAP1,
Species
human
MISSION® esiRNA, targeting mouse Dmap1,
Species
mouse