E2F1
E2F transcription factor 1
Synonyms:
E2F-1, RBAP1, RBBP3, RBP3
Species:
Human E2F1 (1869), Mouse E2f1 (13555), Rat E2f1 (399489), chicken E2F1 (396142), Thale Cress E2F1 (832283), naked mole-rat E2f1 (101717980), Horse E2F1 (100069192), cow E2F1 (535369), sheep E2F1 (101117526), dog E2F1 (485839) ...More
UniProtKB ID:
Gene ID:
- Human(1869) Summary: The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F2 and E2F3, have an additional cyclin binding domain. This protein binds preferentially to retinoblastoma protein pRB in a cell-cycle dependent manner. It can mediate both cell proliferation and p53-dependent/independent apoptosis. [provided by RefSeq, Jul 2008]
- Mouse(13555) E2F transcription factor 1
- Rat(399489) E2F transcription factor 1
- chicken(396142) E2F transcription factor 1
- Thale Cress(832283) E2F transcription factor 1
- naked mole-rat(101717980) E2F transcription factor 1
- Horse(100069192) E2F transcription factor 1
- cow(535369) E2F transcription factor 1
- sheep(101117526) E2F transcription factor 1
- dog(485839) E2F transcription factor 1
- domestic guinea pig(100729531) E2F transcription factor 1
- domestic cat(101098454) E2F transcription factor 1
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-E2F1 Antibody, clone 5Z5U3, Rabbit Monoclonal, ,
Species Reactivity
human, rat
Application
immunoprecipitation (IP)
western blot
western blot
Anti-E2F-1 Antibody, clones KH20 and KH95, Upstate®, from mouse,
Species Reactivity
xenopus, human
Application
immunoprecipitation (IP)
western blot
western blot
Monoclonal Anti-E2F1 antibody produced in mouse, clone 2E10, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
proximity ligation assay
western blot
proximity ligation assay
western blot
Anti-E2F1 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse
Application
ELISA
western blot
western blot
Anti-E2F1, (N-terminal) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
dog, guinea pig, horse, human, mouse, rabbit, rat
Application
western blot
Proteins
Product Number
Description
Species