EIF4EBP1
eukaryotic translation initiation factor 4E binding protein 1
Synonyms:
4E-BP1, 4EBP1, BP-1, PHAS-I
Species:
Human EIF4EBP1 (1978), Mouse Eif4ebp1 (13685), Rat Eif4ebp1 (116636), domestic cat EIF4EBP1 (101088571), Goat EIF4EBP1 (100861097), dog EIF4EBP1 (475590), chicken EIF4EBP1 (426773), domestic guinea pig Eif4ebp1 (100733182), Zebrafish eif4ebp1 (799566), sheep EIF4EBP1 (101111426) ...More
UniProtKB ID:
Gene ID:
- Human(1978) Summary: This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation. [provided by RefSeq, Jul 2008]
- Mouse(13685) eukaryotic translation initiation factor 4E binding protein 1
- Rat(116636) eukaryotic translation initiation factor 4E binding protein 1
- domestic cat(101088571) eukaryotic translation initiation factor 4E binding protein 1
- Goat(100861097) eukaryotic translation initiation factor 4E binding protein 1
- dog(475590) eukaryotic translation initiation factor 4E binding protein 1
- chicken(426773) eukaryotic translation initiation factor 4E binding protein 1
- domestic guinea pig(100733182) eukaryotic translation initiation factor 4E binding protein 1
- Zebrafish(799566) eukaryotic translation initiation factor 4E binding protein 1
- sheep(101111426) eukaryotic translation initiation factor 4E binding protein 1
- cow(509613) eukaryotic translation initiation factor 4E binding protein 1
- naked mole-rat(101710614) eukaryotic translation initiation factor 4E binding protein 1
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Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-EIF4EBP1 antibody produced in mouse, clone 4F3-H2, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence
proximity ligation assay
western blot
immunofluorescence
proximity ligation assay
western blot
Monoclonal Anti-EIF4EBP1 antibody produced in mouse, clone 1F7, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
western blot
Anti-4E-BP1 Antibody, clone 1I3 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human, rat
Application
affinity binding assay
immunocytochemistry
immunohistochemistry
western blot
immunocytochemistry
immunohistochemistry
western blot
Anti-phospho-4E BP1 (Ser83) Antibody, clone CM14D3, ,
Species Reactivity
human, mouse
Application
western blot
Anti-Phospho-EIF4EBP1-T37/46 antibody produced in rabbit, ,
Species Reactivity
human, mouse
Application
western blot
Proteins
Product Number
Description
Species
4EBP1, GST tagged human, recombinant, expressed in E. coli, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human
4EBP1, His tagged human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human