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ELAVL1

ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)

Synonyms:
ELAV1, HUR, Hua, MelG
Species:
UniProtKB ID:
Gene ID:
  • Human(1994) Summary: The protein encoded by this gene is a member of the ELAVL family of RNA-binding proteins that contain several RNA recognition motifs, and selectively bind AU-rich elements (AREs) found in the 3' untranslated regions of mRNAs. AREs signal degradation of mRNAs as a means to regulate gene expression, thus by binding AREs, the ELAVL family of proteins play a role in stabilizing ARE-containing mRNAs. This gene has been implicated in a variety of biological processes and has been linked to a number of diseases, including cancer. It is highly expressed in many cancers, and could be potentially useful in cancer diagnosis, prognosis, and therapy. [provided by RefSeq, Sep 2012]
  • Mouse(15568) ELAV (embryonic lethal, abnormal vision)-like 1 (Hu antigen R)
  • Rat(363854) ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)
  • Domestic Rabbit(100353220) ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)
  • Horse(100060819) ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)
  • Zebrafish(30736) ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)
  • dog(611201) ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)
  • naked mole-rat(101713794) ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)
  • domestic cat(101094402) ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)
  • domestic guinea pig(100735972) ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)
  • sheep(100307040) ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)
  • chicken(395637) ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)
  • cow(617316) ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)

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  • Custom Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti- HuR/ELAVL1 antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
western blot
Anti-HuR/ELAVL1 antibody produced in rabbit, ,
Species Reactivity
human, mouse
Application
immunofluorescence
immunohistochemistry

western blot
Anti-HuR/ELAVL1 antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
immunofluorescence
immunohistochemistry

western blot
Anti-phospho HuR (Ser221) Antibody, from rabbit, purified by affinity chromatography,
Species Reactivity
xenopus, bovine, chicken, human, mouse, porcine
Application
inhibition assay
western blot
RIPAb+ HuR - RIP Validated Antibody and Primer Set, from rabbit,
Species Reactivity
human, mouse, rat
Application
RIP
immunocytochemistry

immunohistochemistry

immunoprecipitation (IP)

western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Elavl1,
Species
mouse
MISSION® esiRNA, targeting human ELAVL1,
Species
human