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ERCC6

excision repair cross-complementing rodent repair deficiency, complementation group 6

Synonyms:
ARMD5, CKN2, COFS, COFS1, CSB, RAD26, UVSS1
Species:
UniProtKB ID:
Gene ID:
  • Human(2074) Summary: This gene encodes a DNA-binding protein that is important in transcription-coupled excision repair. The encoded protein has ATP-stimulated ATPase activity, interacts with several transcription and excision repair proteins, and may promote complex formation at DNA repair sites. Mutations in this gene are associated with Cockayne syndrome type B and cerebrooculofacioskeletal syndrome 1. Naturally-occurring readthrough transcription occurs between this gene and the adjacent PGBD3 gene (GeneID:267004), and results in a fusion protein that shares sequence with the product of each individual gene. The readthrough locus is represented by GeneID:101243544. [provided by RefSeq, Mar 2013]
  • Mouse(319955) excision repair cross-complementing rodent repair deficiency, complementation group 6
  • Rat(306274) excision repair cross-complementing rodent repair deficiency, complementation group 6
  • naked mole-rat(101712293) excision repair cross-complementing rodent repair deficiency, complementation group 6
  • Horse(100062916) excision repair cross-complementing rodent repair deficiency, complementation group 6
  • sheep(101117559) excision repair cross-complementing rodent repair deficiency, complementation group 6
  • domestic guinea pig(100719487) excision repair cross-complementing rodent repair deficiency, complementation group 6
  • chicken(423785) excision repair cross-complementing rodent repair deficiency, complementation group 6
  • Zebrafish(560477) excision repair cross-complementing rodent repair deficiency, complementation group 6
  • domestic cat(101092399) excision repair cross-complementing rodent repair deficiency, complementation group 6
  • dog(477747) excision repair cross-complementing rodent repair deficiency, complementation group 6
  • cow(522908) excision repair cross-complementing rodent repair deficiency, complementation group 6

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-ERCC6 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
immunofluorescence
immunohistochemistry

immunoprecipitation (IP)

western blot
Anti-ERCC6 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
Anti-CSB (ERCC6) Antibody, clone ICSB-3H8, clone 1CSB-3H8, from mouse,
Species Reactivity
human
Application
ChIP
flow cytometry

immunocytochemistry

immunoprecipitation (IP)

western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Ercc6,
Species
mouse
MISSION® esiRNA, targeting human ERCC6,
Species
human