F11
coagulation factor XI
Synonyms:
FXI
Species:
Human F11 (2160), Mouse F11 (109821), Rat F11 (290757), chicken F11 (422723), naked mole-rat F11 (101717554), domestic guinea pig F11 (100715511), Domestic Rabbit F11 (100009596), sheep F11 (101116630), cow F11 (407998), Horse F11 (100056603) ...More
UniProtKB ID:
Gene ID:
- Human(2160) Summary: This gene encodes coagulation factor XI of the blood coagulation cascade. This protein is present in plasma as a zymogen, which is a unique plasma coagulation enzyme because it exists as a homodimer consisting of two identical polypeptide chains linked by disulfide bonds. During activation of the plasma factor XI, an internal peptide bond is cleaved by factor XIIa (or XII) in each of the two chains, resulting in activated factor XIa, a serine protease composed of two heavy and two light chains held together by disulfide bonds. This activated plasma factor XI triggers the middle phase of the intrisic pathway of blood coagulation by activating factor IX. Defects in this factor lead to Rosenthal syndrome, a blood coagulation abnormality. [provided by RefSeq, Jul 2008]
- Mouse(109821) coagulation factor XI
- Rat(290757) coagulation factor XI
- chicken(422723) coagulation factor XI
- naked mole-rat(101717554) coagulation factor XI
- domestic guinea pig(100715511) coagulation factor XI
- Domestic Rabbit(100009596) coagulation factor XI
- sheep(101116630) coagulation factor XI
- cow(407998) coagulation factor XI
- Horse(100056603) coagulation factor XI
- domestic cat(101094340) coagulation factor XI
- domestic cat(493756) coagulation factor XI
- dog(475623) coagulation factor XI
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ELISA
Product Number
Description
Species
Human Coagulation Factor XI ELISA, for serum, plasma and cell culture supernatants,
Species
human
Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-F11 antibody produced in mouse, clone 3C7, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
Anti-F11 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
Anti-F11 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
esiRNA
Product Number
Description
Species