Skip to Content
MilliporeSigma

GCA

grancalcin, EF-hand calcium binding protein

Synonyms:
GCL
Species:
UniProtKB ID:
Gene ID:
  • Human(25801) Summary: This gene product, grancalcin, is a calcium-binding protein abundant in neutrophils and macrophages. It belongs to the penta-EF-hand subfamily of proteins which includes sorcin, calpain, and ALG-2. Grancalcin localization is dependent upon calcium and magnesium. In the absence of divalent cation, grancalcin localizes to the cytosolic fraction; with magnesium alone, it partitions with the granule fraction; and in the presence of magnesium and calcium, it associates with both the granule and membrane fractions, suggesting a role for grancalcin in granule-membrane fusion and degranulation. [provided by RefSeq, Jul 2008]
  • Mouse(227960) grancalcin
  • Rat(295647) grancalcin
  • domestic cat(101098073) grancalcin, EF-hand calcium binding protein
  • dog(608208) grancalcin, EF-hand calcium binding protein
  • sheep(101105979) grancalcin, EF-hand calcium binding protein
  • cow(507139) grancalcin, EF-hand calcium binding protein
  • naked mole-rat(101720587) grancalcin, EF-hand calcium binding protein
  • domestic guinea pig(100717324) grancalcin, EF-hand calcium binding protein

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-GCA antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

western blot
Anti-GCA antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

western blot
Monoclonal Anti-GCA antibody produced in mouse, clone 2F5, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence

western blot
Monoclonal Anti-GCA antibody produced in mouse, clone 2F11, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
Monoclonal Anti-GCA antibody produced in mouse, clone 3D12, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human GCA,
Species
human
MISSION® esiRNA, targeting mouse Gca,
Species
mouse