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GFRA1

GDNF family receptor alpha 1

Synonyms:
GDNFR, GDNFRA, GFR-ALPHA-1, RET1L, RETL1, TRNR1
Species:
UniProtKB ID:
Gene ID:
  • Human(2674) Summary: Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This gene is a candidate gene for Hirschsprung disease. Multiple alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Feb 2009]
  • Mouse(14585) glial cell line derived neurotrophic factor family receptor alpha 1
  • Rat(25454) GDNF family receptor alpha 1
  • sheep(101120125) GDNF family receptor alpha 1
  • cow(534801) GDNF family receptor alpha 1
  • dog(609114) GDNF family receptor alpha 1
  • domestic cat(101085242) GDNF family receptor alpha 1
  • chicken(395994) GDNF family receptor alpha 1
  • naked mole-rat(101699880) GDNF family receptor alpha 1
  • domestic guinea pig(100720930) GDNF family receptor alpha 1

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ELISA

Product Number
Description
Species
Rat GFR alpha-1 ELISA, for serum, plasma and cell culture supernatants,
Species
rat
Human GFR alpha-1 ELISA, for serum, plasma and cell culture supernatants,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-GFRα1 antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry

western blot
Anti-GFRA1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
Anti-GFRA1 antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
immunofluorescence
western blot
Monoclonal Anti-GFRA1 antibody produced in mouse, clone 3E4, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
Monoclonal Anti-GFRA1 antibody produced in mouse, clone 4G3, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence

Proteins

Product Number
Description
Species
GFRA1/GDNFRA human, recombinant, expressed in HEK 293 cells, ≥95% (SDS-PAGE),
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human GFRA1,
Species
human