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GUCA2B

guanylate cyclase activator 2B (uroguanylin)

Synonyms:
GCAP-II, UGN
Species:
UniProtKB ID:
Gene ID:
  • Human(2981) Summary: This gene encodes a member of the guanylin family, and is expressed in the stomach and intestine. This protein functions as an endogenous ligand for the guanylate cyclase-C receptor and stimulates an increase in cyclic GMP, a key component of several intracellular signal transduction pathways. It maybe involved in salt and water secretion into the intestinal lumen as well as the renal tubules, and thus regulate electrolyte homeostasis in these tissues. [provided by RefSeq, Oct 2011]
  • Mouse(14916) guanylate cyclase activator 2b (retina)
  • Rat(64055) guanylate cyclase activator 2B
  • dog(100684829) guanylate cyclase activator 2B (uroguanylin)
  • naked mole-rat(101720311) guanylate cyclase activator 2B (uroguanylin)
  • domestic guinea pig(100135535) guanylate cyclase activator 2b (retina)
  • domestic cat(101092381) guanylate cyclase activator 2B (uroguanylin)
  • Zebrafish(325935) guanylate cyclase activator 2B (uroguanylin)
  • cow(515664) guanylate cyclase activator 2B (uroguanylin)

Custom & Knockdown Gene Products

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Small Molecule - Antagonist

Product Number
Description
Species
Kynurenic acid, ≥98%,
Species
rat, human

Antibodies

Product Number
Description
Species Reactivity
Application
ANTI-GUCA2B (C-TERM) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
human
Application
western blot

Proteins

Product Number
Description
Species
Uroguanylin, ≥90% (HPLC),
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human GUCA2B,
Species
human