GUCA2B
guanylate cyclase activator 2B (uroguanylin)
GCAP-II, UGN
Human GUCA2B (2981), Mouse Guca2b (14916), Rat Guca2b (64055), dog GUCA2B (100684829), naked mole-rat Guca2b (101720311), domestic guinea pig Guca2b (100135535), domestic cat GUCA2B (101092381), Zebrafish guca2b (325935), cow GUCA2B (515664)
- Human(2981) Summary: This gene encodes a member of the guanylin family, and is expressed in the stomach and intestine. This protein functions as an endogenous ligand for the guanylate cyclase-C receptor and stimulates an increase in cyclic GMP, a key component of several intracellular signal transduction pathways. It maybe involved in salt and water secretion into the intestinal lumen as well as the renal tubules, and thus regulate electrolyte homeostasis in these tissues. [provided by RefSeq, Oct 2011]
- Mouse(14916) guanylate cyclase activator 2b (retina)
- Rat(64055) guanylate cyclase activator 2B
- dog(100684829) guanylate cyclase activator 2B (uroguanylin)
- naked mole-rat(101720311) guanylate cyclase activator 2B (uroguanylin)
- domestic guinea pig(100135535) guanylate cyclase activator 2b (retina)
- domestic cat(101092381) guanylate cyclase activator 2B (uroguanylin)
- Zebrafish(325935) guanylate cyclase activator 2B (uroguanylin)
- cow(515664) guanylate cyclase activator 2B (uroguanylin)
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Small Molecule - Antagonist
Antibodies
ANTI-GUCA2B (C-TERM) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
human
western blot