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H2AFZ

H2A histone family, member Z

Synonyms:
H2A.Z-1, H2A.z, H2A/z, H2AZ
Species:
UniProtKB ID:
Gene ID:
  • Human(3015) Summary: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent member of the histone H2A family that is distinct from other members of the family. Studies in mice have shown that this particular histone is required for embryonic development and indicate that lack of functional histone H2A leads to embryonic lethality. [provided by RefSeq, Jul 2008]
  • Mouse(51788) H2A histone family, member Z
  • Rat(58940) H2A histone family, member Z
  • Zebrafish(573415) H2A histone family, member Z
  • cow(287016) H2A histone family, member Z
  • chicken(426361) H2A histone family, member Z
  • dog(478493) H2A histone family, member Z
  • sheep(443235) histone H2A.Z

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-H2AFZ antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunohistochemistry
Anti-acetyl Histone H2A.Z (Lys 5, 7, 11) Antibody, from rabbit, purified by affinity chromatography,
Species Reactivity
human, mouse
Application
ChIP
ELISA

dot blot

immunocytochemistry

western blot
Anti-monomethyl Histone H2A.Z Antibody (Lys 7), from rabbit, purified by affinity chromatography,
Species Reactivity
human
Application
dot blot
immunocytochemistry

immunoprecipitation (IP)

western blot
Anti-Histone H2A.Z Antibody (C-term), from rabbit, purified by affinity chromatography,
Species Reactivity
human
Application
ChIP
ELISA

immunocytochemistry

western blot
Anti-Histone H2A.Z Antibody, serum, Upstate®,
Species Reactivity
human
Application
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse H2afz,
Species
mouse
MISSION® esiRNA, targeting human H2AFZ,
Species
human