HLA-DPA1
major histocompatibility complex, class II, DP alpha 1
Synonyms:
DP(W3), DP(W4), HLA-DP1A, HLADP, HLASB, PLT1
Species:
UniProtKB ID:
Gene ID:
- Human(3113) Summary: HLA-DPA1 belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta (DPB) chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DP molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules. [provided by RefSeq, Jul 2008]
- Zebrafish(553497) HLA-DPA1 protein
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-HLA-DPA1 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-HLA-DP alpha 1 antibody, Rabbit monoclonal, recombinant, expressed in proprietary host, clone SP228, affinity isolated antibody,
Species Reactivity
human
Application
flow cytometry
immunohistochemistry
immunohistochemistry
Anti-HLA-DPA1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-HLA-DPA1 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Monoclonal Anti-HLA-DPA1 antibody produced in mouse, clone 1E3, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
western blot
esiRNA
Product Number
Description
Species