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HLA-DRA

major histocompatibility complex, class II, DR alpha

Synonyms:
HLA-DRA1, MLRW
Species:
Human HLA-DRA (3122)
UniProtKB ID:
P01903, A2BET4, Q30160, Q6IAZ1, Q861I2, Q9TP70
Gene ID:
  • Human(3122) Summary: HLA-DRA is one of the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha and a beta chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. DRA does not have polymorphisms in the peptide binding part and acts as the sole alpha chain for DRB1, DRB3, DRB4 and DRB5. [provided by RefSeq, Jul 2008]

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Antibodies

Product Number
Description
Species Reactivity
Application
SAB4700659
Monoclonal Anti-HLA-DR-FITC antibody produced in mouse, clone MEM-12, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
flow cytometry
SAB4700660
Monoclonal Anti-HLA-DR-DP-PE antibody produced in mouse, clone HL-38, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
flow cytometry
SAB1405944
Anti-HLA-DRA antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
SAB1409196
Anti-HLA-DRA antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
SAB4700731
Monoclonal Anti-HLA-DR antibody produced in mouse, clone L243, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
dog, human, nonhuman primates
Application
FUNC
flow cytometry
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
western blot

esiRNA

Product Number
Description
Species
EHU218921
MISSION® esiRNA, targeting human HLA-DRA (1),
Species
human
EHU226621
MISSION® esiRNA, targeting human HLA-DRA (2),
Species
human