IL12B
interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)
Synonyms:
CLMF, CLMF2, IL-12B, NKSF, NKSF2
Species:
Human IL12B (3593), Mouse Il12b (16160), Rat Il12b (64546), cow IL12B (281857), chicken IL12B (404671), Horse IL12B (100034222), sheep IL12B (443472), naked mole-rat Il12b (101701309), domestic cat IL12B (768273), dog IL12B (403976)
UniProtKB ID:
Gene ID:
- Human(3593) Summary: This gene encodes a subunit of interleukin 12, a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. Interleukin 12 is a disulfide-linked heterodimer composed of the 40 kD cytokine receptor like subunit encoded by this gene, and a 35 kD subunit encoded by IL12A. This cytokine is expressed by activated macrophages that serve as an essential inducer of Th1 cells development. This cytokine has been found to be important for sustaining a sufficient number of memory/effector Th1 cells to mediate long-term protection to an intracellular pathogen. Overexpression of this gene was observed in the central nervous system of patients with multiple sclerosis (MS), suggesting a role of this cytokine in the pathogenesis of the disease. The promoter polymorphism of this gene has been reported to be associated with the severity of atopic and non-atopic asthma in children. [provided by RefSeq, Jul 2008]
- Mouse(16160) interleukin 12b
- Rat(64546) interleukin 12B
- cow(281857) interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)
- chicken(404671) interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)
- Horse(100034222) interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)
- sheep(443472) interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)
- naked mole-rat(101701309) interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)
- domestic cat(768273) interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)
- dog(403976) interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)
- domestic guinea pig(100135554) interleukin 12b
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ELISA
Product Number
Description
Species
Human IL-12 p40 ELISA Kit, for serum, plasma, cell culture supernatant and urine,
Species
human
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-IL12B/IL12P40 (AB2) antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
mouse, rat
Application
ELISA
western blot
western blot
Anti-IL12B/IL12P40 (AB1) antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-IL-12/IL-23 p40 (mouse), PE, clone C17.8 Antibody, clone C17.8, from rat, PE,
Species Reactivity
mouse
Application
flow cytometry
Anti-IL-12/IL-23 p40 (mouse), PE, clone C17.8 Antibody, clone C17.8, from rat, PE,
Species Reactivity
mouse
Application
flow cytometry
Monoclonal Anti-IL12B antibody produced in mouse, clone 2H6, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
western blot
Proteins
Product Number
Description
Species
IL-12p80 human, recombinant, expressed in (BTI-Tn-5B1-4) High-5 Insect Cells, ≥95% (SDS-PAGE), ≥95% (HPLC), suitable for cell culture,
Species
human
Interleukin-12 from mouse, ≥97% (SDS-PAGE), recombinant, expressed in baculovirus infected Sf21 cells, lyophilized powder, suitable for cell culture,
Species
mouse
Interleukin-12 human, ≥97% (SDS-PAGE and N-terminal analysis), recombinant, expressed in baculovirus infected Sf21 cells, lyophilized powder, suitable for cell culture,
Species
human