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IL21R

interleukin 21 receptor

Synonyms:
CD360, NILR
Species:
UniProtKB ID:
Gene ID:
  • Human(50615) Summary: The protein encoded by this gene is a cytokine receptor for interleukin 21 (IL21). It belongs to the type I cytokine receptors, and has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the receptors for interleukin 2, 4, 7, 9, and 15. This receptor transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules, including JAK1, JAK3, STAT1, and STAT3. Knockout studies of a similar gene in mouse suggest a role for this gene in regulating immunoglobulin production. Three alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2010]
  • Mouse(60504) interleukin 21 receptor
  • Rat(308977) interleukin 21 receptor
  • sheep(100820753) interleukin 21 receptor
  • chicken(416586) interleukin 21 receptor
  • Horse(100066814) interleukin 21 receptor
  • domestic cat(101096026) interleukin 21 receptor
  • domestic guinea pig(100721842) interleukin 21 receptor
  • cow(617967) interleukin 21 receptor
  • dog(608011) interleukin 21 receptor
  • naked mole-rat(101701307) interleukin 21 receptor
  • Zebrafish(100134976) interleukin 21 receptor

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ELISA

Product Number
Description
Species
Human IL21R / Interleukin-21 Receptor ELISA Kit, ,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-IL-21 Receptor (ab2) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence

western blot
Anti-IL21R antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human IL21R,
Species
human