IL4R
interleukin 4 receptor
Synonyms:
CD124, IL-4RA, IL4RA
Species:
Human IL4R (3566), Rat Il4r (25084), cow IL4R (404154), domestic guinea pig Il4r (100721566), sheep IL4R (101109063), Horse IL4R (791252), domestic cat IL4R (101096277), Zebrafish il4r (503594), dog IL4R (489957), Domestic Rabbit IL4R (100337721) ...More
UniProtKB ID:
Gene ID:
- Human(3566) Summary: This gene encodes the alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE production. The encoded protein also can bind interleukin 4 to promote differentiation of Th2 cells. A soluble form of the encoded protein can be produced by proteolysis of the membrane-bound protein, and this soluble form can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells. Allelic variations in this gene have been associated with atopy, a condition that can manifest itself as allergic rhinitis, sinusitus, asthma, or eczema. Polymorphisms in this gene are also associated with resistance to human immunodeficiency virus type-1 infection. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Apr 2012]
- Rat(25084) interleukin 4 receptor
- cow(404154) interleukin 4 receptor
- domestic guinea pig(100721566) interleukin 4 receptor
- sheep(101109063) interleukin 4 receptor
- Horse(791252) interleukin 4 receptor
- domestic cat(101096277) interleukin 4 receptor
- Zebrafish(503594) interleukin 4 receptor
- dog(489957) interleukin 4 receptor
- Domestic Rabbit(100337721) interleukin 4 receptor
- chicken(416585) interleukin 4 receptor
- naked mole-rat(101704138) interleukin 4 receptor
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ELISA
Product Number
Description
Species
Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-IL4R antibody produced in mouse, clone 1D3, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
Anti-IL-4R antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse
Application
ELISA
immunofluorescence
western blot
immunofluorescence
western blot
Anti-Interleukin-4 Soluble Receptor antibody produced in goat, IgG fraction of antiserum, lyophilized powder,
Species Reactivity
human
Application
ELISA
neutralization
western blot
neutralization
western blot
Anti-IL4R antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
Anti-IL4R antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
flow cytometry
western blot
western blot
esiRNA
Product Number
Description
Species