IRS2
insulin receptor substrate 2
Synonyms:
IRS-2
Species:
Human IRS2 (8660), Mouse Irs2 (384783), Rat Irs2 (29376), Zebrafish irs2 (572001), naked mole-rat Irs2 (101719081), Horse IRS2 (100146249), dog IRS2 (485548), domestic cat IRS2 (101095791), domestic cat IRS2 (100271863), domestic guinea pig Irs2 (100730395) ...More
UniProtKB ID:
Gene ID:
- Human(8660) Summary: This gene encodes the insulin receptor substrate 2, a cytoplasmic signaling molecule that mediates effects of insulin, insulin-like growth factor 1, and other cytokines by acting as a molecular adaptor between diverse receptor tyrosine kinases and downstream effectors. The product of this gene is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation, as well as by an interleukin 4 receptor-associated kinase in response to IL4 treatment. [provided by RefSeq, Jul 2008]
- Mouse(384783) insulin receptor substrate 2
- Rat(29376) insulin receptor substrate 2
- Zebrafish(572001) insulin receptor substrate 2
- naked mole-rat(101719081) insulin receptor substrate 2
- Horse(100146249) insulin receptor substrate 2
- dog(485548) insulin receptor substrate 2
- domestic cat(101095791) insulin receptor substrate 2
- domestic cat(100271863) insulin receptor substrate 2
- domestic guinea pig(100730395) insulin receptor substrate 2
- cow(100300012) insulin receptor substrate 2
- chicken(428017) insulin receptor substrate 2
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-IRS2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
Anti-IRS-2 Antibody, clone 9.5.2, clone 9.5.2, from mouse,
Species Reactivity
mouse, rat
Application
western blot
Anti-phospho-IRS-2 (Ser388) Antibody, from rabbit, purified by affinity chromatography,
Species Reactivity
human
Application
inhibition assay
western blot
western blot