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Merck

ITGAV

integrin, alpha V

Synonyms:
CD51, MSK8, VNRA, VTNR
Species:
Human ITGAV (3685), Mouse Itgav (16410), Rat Itgav (296456), dog ITGAV (488437), naked mole-rat Itgav (101717672), domestic guinea pig Itgav (100728575), domestic cat ITGAV (101085820), chicken ITGAV (396420), Zebrafish itgav (100151255), Domestic Rabbit ITGAV (100008956) ...More
UniProtKB ID:
P06756, A0AV67, B0LPF4, B7Z883, D3DPG8, E7EWZ6, Q53SK4, Q59EB7
Gene ID:
  • Human(3685) Summary: This gene encodes a protein that is a member of the integrin superfamily. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein undergoes post-translational cleavage to yield disulfide-linked heavy and light chains that combine with multiple integrin beta chains to form different integrins. This protein has been shown to heterodimerize with beta 1, beta 3, beta 5, beta 6, and beta 8; the heterodimer of alpha v and beta 3 is the Vitronectin receptor. This protein interacts with several extracellular matrix proteins to mediate cell adhesion and may play a role in cell migration. It is proposed that this protein may regulate angiogenesis and cancer progression. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, May 2013]
  • Mouse(16410) integrin alpha V
  • Rat(296456) integrin, alpha V
  • dog(488437) integrin, alpha V
  • naked mole-rat(101717672) integrin, alpha V
  • domestic guinea pig(100728575) integrin, alpha V
  • domestic cat(101085820) integrin, alpha V
  • chicken(396420) integrin, alpha V
  • Zebrafish(100151255) integrin, alpha V
  • Domestic Rabbit(100008956) integrin, alpha V
  • cow(281875) integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)
  • sheep(443143) integrin, alpha V
  • Horse(100068706) integrin, alpha V

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Small Molecule - Antagonist

Product Number
Description
Species
G1269
Gly-Arg-Gly-Asp-Ser-Pro-Lys, ≥97% (HPLC),
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
HPA004856
Anti-ITGAV antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
SAB1406048
Anti-ITGAV antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
proximity ligation assay
western blot
SAB5702151
Anti-Integrin alpha V (ITGAV/CD51) Antibody, clone 10T9N2, Rabbit Monoclonal, ,
Species Reactivity
human, rat
Application
flow cytometry
immunohistochemistry
western blot
MAB1978-I
Anti-Integrin αV Antibody, clone LM142, ,
Species Reactivity
human
Application
flow cytometry
immunofluorescence
immunohistochemistry
neutralization
MAB2021Z
Anti-Integrin αV Antibody, extracellular, clone AV1, azide free, culture supernatant, clone AV1, Chemicon®,
Species Reactivity
human
Application
flow cytometry
western blot

Proteins

Product Number
Description
Species
CC102A
Human Integrin αVβ3, Octyl-β-D-glucopyranoside Formulation, ,
Species
human
CC101
Human Integrin αVβ3 Protein, Triton X-100 Formulation, ,
Species
human

esiRNA

Product Number
Description
Species
EMU051281
MISSION® esiRNA, targeting mouse Itgav,
Species
mouse
EHU002301
MISSION® esiRNA, targeting human ITGAV,
Species
human