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KANK1

KN motif and ankyrin repeat domains 1

Synonyms:
ANKRD15, CPSQ2, KANK
Species:
UniProtKB ID:
Gene ID:
  • Human(23189) Summary: The protein encoded by this gene belongs to the Kank family of proteins, which contain multiple ankyrin repeat domains. This family member functions in cytoskeleton formation by regulating actin polymerization. This gene is a candidate tumor suppressor for renal cell carcinoma. Mutations in this gene cause cerebral palsy spastic quadriplegic type 2, a central nervous system development disorder. A t(5;9) translocation results in fusion of the platelet-derived growth factor receptor beta gene (PDGFRB) on chromosome 5 with this gene in a myeloproliferative neoplasm featuring severe thrombocythemia. Alternative splicing of this gene results in multiple transcript variants. A related pseuodgene has been identified on chromosome 20. [provided by RefSeq, Mar 2012]
  • Mouse(107351) KN motif and ankyrin repeat domains 1
  • Rat(309429) KN motif and ankyrin repeat domains 1
  • sheep(101109511) KN motif and ankyrin repeat domains 1
  • domestic cat(101101346) KN motif and ankyrin repeat domains 1
  • Horse(100050757) KN motif and ankyrin repeat domains 1
  • cow(534869) KN motif and ankyrin repeat domains 1
  • dog(100687276) KN motif and ankyrin repeat domains 1
  • Zebrafish(777729) KN motif and ankyrin repeat domains 1
  • chicken(395475) KN motif and ankyrin repeat domains 1
  • domestic guinea pig(100727320) KN motif and ankyrin repeat domains 1
  • naked mole-rat(101702127) KN motif and ankyrin repeat domains 1

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-KANK1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-KANK1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
Anti-KANK1 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse
Application
ELISA
immunofluorescence

immunohistochemistry

western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Kank1,
Species
mouse
MISSION® esiRNA, targeting human KANK1,
Species
human
MISSION® esiRNA, targeting human KANK1,
Species
human