KDELR3
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
Synonyms:
ERD2L3
Species:
Human KDELR3 (11015), Mouse Kdelr3 (105785), Rat Kdelr3 (315131), chicken KDELR3 (418026), naked mole-rat Kdelr3 (101706113), Zebrafish kdelr3 (393613), domestic guinea pig Kdelr3 (100727776), domestic cat KDELR3 (101080390), cow KDELR3 (509687), dog KDELR3 (474509)
UniProtKB ID:
Gene ID:
- Human(11015) Summary: This gene encodes a member of the KDEL endoplasmic reticulum protein retention receptor family. Retention of resident soluble proteins in the lumen of the endoplasmic reticulum (ER) is achieved in both yeast and animal cells by their continual retrieval from the cis-Golgi, or a pre-Golgi compartment. Sorting of these proteins is dependent on a C-terminal tetrapeptide signal, usually lys-asp-glu-leu (KDEL) in animal cells, and his-asp-glu-leu (HDEL) in S. cerevisiae. This process is mediated by a receptor that recognizes, and binds the tetrapeptide-containing protein, and returns it to the ER. In yeast, the sorting receptor encoded by a single gene, ERD2, is a seven-transmembrane protein. Unlike yeast, several human homologs of the ERD2 gene, constituting the KDEL receptor gene family, have been described. KDELR3 was the third member of the family to be identified. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
- Mouse(105785) KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
- Rat(315131) KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
- chicken(418026) KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
- naked mole-rat(101706113) KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
- Zebrafish(393613) KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
- domestic guinea pig(100727776) KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
- domestic cat(101080390) KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
- cow(509687) KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
- dog(474509) KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-KDELR3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-KDELR3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence