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LEPR

leptin receptor

Synonyms:
CD295, LEP-R, LEPRD, OB-R, OBR
Species:
UniProtKB ID:
Gene ID:
  • Human(3953) Summary: The protein encoded by this gene belongs to the gp130 family of cytokine receptors that are known to stimulate gene transcription via activation of cytosolic STAT proteins. This protein is a receptor for leptin (an adipocyte-specific hormone that regulates body weight), and is involved in the regulation of fat metabolism, as well as in a novel hematopoietic pathway that is required for normal lymphopoiesis. Mutations in this gene have been associated with obesity and pituitary dysfunction. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. It is noteworthy that this gene and LEPROT gene (GeneID:54741) share the same promoter and the first 2 exons, however, encode distinct proteins (PMID:9207021).[provided by RefSeq, Nov 2010]
  • Mouse(16847) leptin receptor
  • Rat(24536) leptin receptor
  • domestic cat(101085646) leptin receptor
  • Zebrafish(567241) leptin receptor
  • chicken(374223) leptin receptor
  • sheep(443264) leptin receptor
  • domestic guinea pig(100725434) leptin receptor
  • naked mole-rat(101705981) leptin receptor
  • Horse(100033894) leptin receptor
  • cow(497205) leptin receptor
  • dog(450207) leptin receptor

Custom & Knockdown Gene Products

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  • Custom Gene Products

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ELISA

Product Number
Description
Species
Mouse Lepr / Leptin Receptor ELISA Kit, ,
Species
mouse

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-LEPR antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-Leptin Receptor antibody produced in goat, affinity isolated antibody, lyophilized powder,
Species Reactivity
mouse
Application
flow cytometry
immunohistochemistry

western blot
Anti-Leptin Receptor antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunohistochemistry

western blot
Anti-Leptin Receptor Antibody, clone 6I0O4, Rabbit Monoclonal, ,
Species Reactivity
human, rat
Application
immunohistochemistry
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human LEPR,
Species
human
MISSION® esiRNA, targeting human LEPR (2),
Species
human
MISSION® esiRNA, targeting mouse Lepr,
Species
mouse